Excellent pharmacy blood disorder ITP health advices by Arthur Nathaniel Billings? What is ITP? Immune thrombocytopenia (formerly known as idiopathic thrombocytopenic purpura) is a medical term for an autoimmune disorder (immune) causing a shortage of platelets (thrombocytopenia) and bruising (purpura). What is the cause of ITP? ITP is an autoimmune disease in which the immune system mistakes the platelets as being foreign and destroys them. It can follow a virus, vaccination or certain medications, but for most people the cause is unknown.
Arthur Nathaniel Billings on blood disorder ITP treatments : What is the incidence of ITP? In the USA about 3,000 to 4,000 of the population have ITP at any one time, and it is not more prevalent in any particular racial or ethnic group. What are the symptoms of ITP? Some people with ITP, especially those with a count over 50, may have no symptoms at all, and their ITP only noticed during a routine blood test. Even people with very low counts, can sometimes have few symptoms.
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What causes ITP? ITP is an autoimmune disease. In some cases, this is due to a self-reacting antibody binding to the surface of the platelets, causing both to be removed by cells in the spleen and elsewhere. However, other immune abnormalities have been found in some patients with ITP that affect lymphocytes (a type of white cell) or megakaryocytes (the precursor cells of platelets). These differences may help explain why patients vary in their response to treatment. Why some people develop this “autoimmune” process and others do not is not fully understood. In some individuals, a viral infection may act as an environmental trigger to the process and your doctors may test for triggers such as infection when you are first assessed.
Careful review of your medications: Historically, a bone marrow aspiration was required to make a diagnosis of ITP. It may not be absolutely necessary in the face of a positive antiplatelet antibody test, but it is still commonly done to look at the production of platelets and to rule out any abnormal cells the marrow may be producing that could lower platelet counts. A bone marrow aspiration is necessary for a diagnosis if the antiplatelet antibody testing is negative. See even more information at Arthur Nathaniel Billings.
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Thrombocytopenia means a decreased number of platelets in the blood. Purpura refers to the purple discoloring of the skin, as with a bruise. ITP is a fairly common blood disorder that both children and adults can develop. There are two forms of ITP: Acute thrombocytopenic purpura. This usually affects young children, ages 2 to 6 years old. The symptoms may follow a viral illness, such as chickenpox. Acute ITP usually starts suddenly and the symptoms usually disappear in less than 6 months, often within a few weeks. Treatment is often not needed. The disorder usually does not recur. Acute ITP is the most common form of the disorder.